4.1 What are Enzymes?

  • Enzymes: Biological catalysts made of proteins.
  • Properties:
    • Speed up reactions.
    • Not used up in the reaction.
    • Specific to one substrate.

4.2 Enzyme Action

  • Lock and Key Model: Enzymes have an active site where the substrate fits.

4.3 Factors Affecting Enzyme Activity

  • Temperature: Higher temperature increases enzyme activity until optimum temperature (~37°C), after which denaturation occurs.
  • pH: Each enzyme has an optimum pH. Extreme pH can denature enzymes.
  • Substrate Concentration: Increases enzyme activity until saturation (all active sites are occupied).

4.4 Enzymes in Metabolic Reactions

  • Examples:
    • Amylase: Breaks down starch to maltose.
    • Protease: Breaks down proteins to amino acids.
    • Lipase: Breaks down fats to fatty acids and glycerol.

4.5 Denaturation

  • Denaturation: Irreversible change in enzyme shape due to high temperature or extreme pH.